Dr. Matthias Truttmann is an Assistant Professor in the Department of Molecular and Integrative Physiology and a Research Assistant Professor at the Institute of Gerontology at the University of Michigan Medical School. He holds a BSc, MS, and PhD from the Biozentrum, University of Basel, Switzerland, with postdoctoral fellowships at the Whitehead Institute for Biomedical Research at MIT and Boston Children’s Hospital/Harvard Medical School. Dr. Truttmann’s research centers on the post-translational regulation of chaperone function, particularly the role of protein AMPylation in aging and aging-associated diseases, protein aggregation, and ER quality control. He has secured numerous competitive grants as both principal investigator and mentor, including multi-year NIH and foundation awards. Dr. Truttmann is active in peer review, holds editorial positions, and serves as reviewer for high-impact journals. With a strong record of mentorship at all academic levels, he has guided dozens of undergraduates, graduate students, and postdoctoral fellows. Recognized by multiple awards, Dr. Truttmann’s lab uses a holistic multi-model approach to study proteostasis regulation and the biology of aging, while developing small molecules and nanobodies to exploit cellular mechanisms with the goal to increase human health.

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